Ketamine Therapy Blog — Mental Health Insights & Treatment Guides

Expert insights on ketamine therapy, depression, anxiety, PTSD, and mental health treatment — updated regularly by the Isha Health clinical team.

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Psychedelics for addiction — Nora Volkow at APA 2026

Volkow on Psychedelics for Addiction: APA 2026 Notes

News

At APA 2026, NIDA Director Nora Volkow walked through evidence that psilocybin may help with alcohol use disorder, smoking cessation, and cocaine use disorder.

How to choose a safe ketamine clinic guide for 2026

How to Choose a Safe Ketamine Clinic in 2026

Guides

A 2024 study found ketamine clinics vary widely in safety standards. Here is a patient-focused guide to choosing a safe provider: what to look for, red flags.

Ketamine for OCD — Stanford randomized controlled trial

Ketamine for OCD: Stanford Trial Shows 3-Week Effect

News

Stanford researchers presented unpublished APA 2026 data showing a single ketamine infusion dramatically reduces OCD symptoms — with effects lasting 3 weeks.

Scaling interventional psychiatry — the access problem in mental health care

Why Most People Can't Access Modern Depression Treatments

News

TMS, ketamine, and other interventional psychiatry treatments work, but most patients can't access them. Notes from an APA 2026 panel on the bottleneck.

Antidepressant effect size — 40 years of research, modest improvement

The 40-Year Antidepressant Plateau: APA 2026 Findings

News

At APA 2026, a leading depression researcher said: modern antidepressants are only modestly better than placebo, and 40 years of new drugs haven't changed it.

Vagus nerve stimulation for treatment-resistant depression — APA 2026 recap

Vagus Nerve Stimulation for Depression: What It Is

News

Vagus nerve stimulation (VNS) is an implanted treatment for depression that hasn't responded to multiple medications. What it is and who it helps.

Ketamine sleep improvement through BDNF and slow wave activity in depression

How Ketamine Improves Sleep in Depression

Research

Research reveals that ketamine-induced BDNF increases drive slow wave activity changes during sleep, creating a plasticity-sleep feedback loop that sustains.

APA 2026 Annual Meeting recap — what psychiatrists discussed about ketamine, OCD, and depression treatment

APA 2026 Recap: Ketamine, OCD, and What Psychiatry Discussed

News

A physician's plain-English notes from the American Psychiatric Association 2026 meeting — what the field is saying about antidepressants, ketamine, and OCD.

Ketamine placebo problem and blinding challenges in clinical trials

The Ketamine Placebo Problem: What One Unusual Trial Finds

Research

A controversial trial found ketamine no better than placebo, sparking debate about blinding in ketamine research.

Ketamine and TMS combined treatment research for depression

Ketamine + TMS: The Future of Combined Treatment?

Research

Preliminary research explores combining ketamine's neuroplastic priming with TMS neuromodulation. Here is what early data suggests about this dual treatment.

Ketamine safety during pregnancy and perinatal mental health review

Is Ketamine Safe During Pregnancy?

Safety

A 2026 PMC review and 2024 pregnancy safeguards study examine ketamine safety in perinatal mental health.

Ketamine therapy research for veterans with PTSD and depression

Ketamine for Veterans: What the Research Shows

Research

A 2024 meta-analysis and 2026 retrospective report examine ketamine therapy for veterans with PTSD and depression.

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