Ketamine Therapy Blog — Mental Health Insights & Treatment Guides
Expert insights on ketamine therapy, depression, anxiety, PTSD, and mental health treatment — updated regularly by the Isha Health clinical team.
Ketamine vs. Psilocybin for Neuroplasticity: How Psychedelics Reshape the Brain
A landmark Cell Reports study found that psychedelics including ketamine and psilocybin promote structural and functional neural plasticity.
Who Responds Best to Ketamine? What Research Says About Treatment Predictors
Research is identifying clinical predictors of ketamine response in treatment-resistant depression, including BMI, family history, and anxiety features.
Ketamine and the Gut-Brain Axis: Could Your Microbiome Influence Antidepressant Response?
Emerging research suggests ketamine may influence gut microbiome composition, and that the gut-brain axis could play a role in its antidepressant effects.
MDMA-Assisted Therapy for PTSD: What the Phase 3 Trial Showed
A Phase 3 trial published in Nature Medicine found that MDMA-assisted therapy produced significant improvements in severe PTSD.
Psilocybin for Depression: What the COMPASS Pathways Phase 2b Trial Found
The largest psilocybin trial for treatment-resistant depression, published in the New England Journal of Medicine, showed significant results at the 25mg dose.
Ketamine for Chronic Pain and Depression: Treating Two Conditions Through One Mechanism
Chronic pain and depression co-occur in up to 50% of patients. Learn how ketamine targets shared neural pathways to treat both conditions simultaneously.
Ketamine Long-Term Safety: What a Systematic Review of Side Effects Reveals
A Lancet Psychiatry systematic review examined ketamine side effects across clinical studies. What physicians and patients should know about long-term safety.
Ketamine and Sleep: How Slow Wave Changes May Signal Brain Healing in Depression
Research links ketamine's antidepressant effects to changes in slow wave sleep and BDNF, suggesting that sleep architecture improvements may reflect underlying.
How Long Do Ketamine's Antidepressant Effects Last? What Repeated-Dose Research Reveals
Research on repeated ketamine infusions shows antidepressant effects can last days to weeks after treatment.
Ketamine and Alcohol Use Disorder: Can It Reduce Cravings and Support Recovery?
A landmark study found that combining ketamine with memory reactivation significantly reduced drinking in people with alcohol use disorder.
Ketamine for Postpartum Depression: Could Rapid-Acting Treatment Help New Mothers?
Postpartum depression affects up to 1 in 5 new mothers. See how emerging research on ketamine's rapid antidepressant action could fill a critical treatment gap.
Ketamine and Neuroinflammation: How Anti-Inflammatory Effects May Drive Antidepressant Response
Emerging research suggests ketamine may reduce neuroinflammation by lowering pro-inflammatory cytokines like IL-1β and IL-6, offering a new lens on how it.
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