Ketamine Therapy Blog — Mental Health Insights & Treatment Guides

Expert insights on ketamine therapy, depression, anxiety, PTSD, and mental health treatment — updated regularly by the Isha Health clinical team.

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Ketamine chronic pain depression research - treating comorbid conditions

Ketamine for Chronic Pain and Depression: Treating Two

Research

Chronic pain and depression frequently co-occur and share overlapping neural pathways. Research suggests ketamine may address both conditions simultaneously through NMDA receptor modulation.

Ketamine long term safety profile - systematic review of side effects

Ketamine Long-Term Safety: What a Systematic Review of

Research

A systematic review in Lancet Psychiatry examined ketamine side effects across clinical studies. Here is what physicians and patients should know about the long-term safety profile.

Ketamine and sleep research - slow wave sleep changes and brain plasticity

Ketamine and Sleep: How Slow Wave Changes May Signal

Research

Research links ketamine's antidepressant effects to changes in slow wave sleep and BDNF, suggesting that sleep architecture improvements may reflect underlying brain plasticity.

How long does ketamine last for depression - research on antidepressant durability

How Long Do Ketamine's Antidepressant Effects Last? What

Research

Research on repeated ketamine infusions shows antidepressant effects can last days to weeks after treatment. Here is what the evidence says about durability and maintenance.

Ketamine alcohol use disorder research - reducing cravings and supporting recovery

Ketamine and Alcohol Use Disorder: Can It Reduce Cravings

Research

A landmark study found that combining ketamine with memory reactivation significantly reduced drinking in people with alcohol use disorder. Here is what the research shows.

Ketamine postpartum depression research - rapid-acting treatment for new mothers

Ketamine for Postpartum Depression: Could Rapid-Acting

Research

Postpartum depression affects up to 1 in 5 new mothers and often requires urgent treatment. Emerging research explores whether ketamine's rapid antidepressant action could fill a critical gap.

Ketamine neuroinflammation research - anti-inflammatory effects on the brain

Ketamine and Neuroinflammation: How Anti-Inflammatory

Research

Emerging research suggests ketamine may reduce neuroinflammation by lowering pro-inflammatory cytokines like IL-1β and IL-6, offering a new lens on how it alleviates depression.

Stressful commute after ketamine infusion in NYC

NYC Ketamine Therapy: At-Home vs. IV Clinic Commutes

Recovering from a ketamine infusion on the NYC subway is dangerous and stressful. Learn why at-home therapy is the safer, more private choice for New Yorkers.

Ketamine for Bipolar Depression: What a Landmark NIMH

Ketamine for Bipolar Depression: What a Landmark NIMH

A 2010 NIMH trial tested ketamine as an add-on treatment for bipolar depression. Here's what Diazgranados et al. found and what it means for patients with treatment-resistant bipolar disorder.

Esketamine vs. Racemic Ketamine: What's the Difference

Esketamine vs. Racemic Ketamine: What's the Difference

Esketamine (Spravato) and racemic ketamine are related but distinct. Here's a comparison of the evidence, mechanisms, and practical differences between these two treatments.

Documentation is an important part of clinical care

‍The Silent Partner: How AI Scribes Are Bringing "Presence" Back to Mental Health Care

Discover how AI scribes like Moco and DeepScribe are reducing burnout and restoring human connection in mental health care. Read the full comparison.

Ketamine-Assisted Psychotherapy: Outcomes from Three

Ketamine-Assisted Psychotherapy: Outcomes from Three

A 2019 study examined outcomes from three large practices offering ketamine-assisted psychotherapy. Here's what the data showed about real-world KAP effectiveness.

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