Ketamine Therapy Blog — Mental Health Insights & Treatment Guides

Expert insights on ketamine therapy, depression, anxiety, PTSD, and mental health treatment — updated regularly by the Isha Health clinical team.

Ketamine + TMS: The Future of Combined Treatment?

May 15, 2026Research

Preliminary research explores combining ketamine's neuroplastic priming with TMS neuromodulation. Here is what early data suggests about this dual treatment.

Is Ketamine Safe During Pregnancy?

May 13, 2026Safety

A 2026 PMC review and 2024 pregnancy safeguards study examine ketamine safety in perinatal mental health.

Ketamine for Veterans: What the Research Shows

May 11, 2026Research

A 2024 meta-analysis and 2026 retrospective report examine ketamine therapy for veterans with PTSD and depression.

Combining Psychotherapy with Ketamine: The Evidence

May 7, 2026Research

A 2025 MDPI review examines the effects of psychotherapy on single and repeated ketamine infusions. Here is what the evidence says about combining molecular.

Using Aroma to Optimize Your Ketamine Session: The Science of Set, Setting, and Smell

May 5, 2026Science of Ketamine

Scent has the most direct biological line to the brain regions ketamine acts on. A practical, evidence-grounded guide to using aroma to optimize set, setting.

The Montreal Model: Longer-Lasting Depression Relief

May 5, 2026Research

McGill University's Montreal Model clinical trial showed a 30% depression score drop sustained for 8+ weeks when combining ketamine with psychotherapy.

Ketamine vs ECT: Head-to-Head Trial Results

May 3, 2026Research

A 2024 secondary analysis in JAMA Network Open compared ketamine to ECT for treatment-resistant depression.

11,000 Patients: At-Home Ketamine Depression Data

Apr 29, 2026Research

Mathai et al. 2024 published real-world data from 11,441 at-home telehealth ketamine patients in the Journal of Affective Disorders.

Esketamine Prevents Postpartum Depression: Meta-Analysis

Apr 29, 2026Research

A 2025 BMC Pregnancy and Childbirth meta-analysis finds perioperative esketamine during C-section significantly reduces postpartum depression incidence.

KARMA-Dep 2: Serial Ketamine Infusions for Inpatient Depression

Apr 29, 2026Research

The KARMA-Dep 2 trial published in JAMA Psychiatry tested serial ketamine infusions as adjunctive therapy for inpatient depression.

Ketamine-Enhanced Prolonged Exposure for PTSD

Apr 29, 2026Research

A 2024 RCT protocol explores ketamine-enhanced prolonged exposure therapy for veterans with PTSD. Here is how combining ketamine with PE may improve trauma.

The Neuroplasticity Window: What to Do After Ketamine

Apr 29, 2026Ketamine Therapy Basics

Ketamine triggers a 24-72 hour neuroplasticity window through BDNF release. Here is a practical guide to maximizing this window for lasting mental health.

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