# Isha Health — Online Ketamine Therapy
> Physician-led at-home ketamine-assisted therapy for depression, anxiety, PTSD, and other mood disorders. Available via telemedicine in AZ, CA, CO, FL, GA, NY, OR, TX, and WA.

## About
Isha Health is a telehealth practice offering personalized ketamine-assisted therapy. Founded by Mai Shimada, MD — double board-certified physician (University of Tokyo MD, Harvard postdoctoral research, INSEAD MBA), with training from the UC Berkeley Center for the Science of Psychedelics and Polaris Insight Center KAP program.

## Clinical Outcomes (Published Data)
Based on 546 patients with validated assessments:
- 88.79% of patients with moderate-to-severe depression show measurable improvement (PHQ-9)
- Mean PHQ-9 score reduction: 10.02 → 4.83 (moderate depression → minimal symptoms)
- 92.64% of anxiety patients reach minimal anxiety levels (GAD-7 ≤ 4)
- Average 1.29 sessions to first measurable improvement
- 99.1% patient retention rate
- 128-day average treatment duration
- 0.92% dropout rate
- Full methodology and limitations: https://isha.health/outcomes

## How It Works
1. 60-minute video consultation with a licensed physician ($350)
2. Personalized treatment plan based on symptoms, history, and goals
3. Oral ketamine prescription sent to compounding pharmacy ($50-150/month)
4. At-home sessions with eye mask, ~2 hours per session
5. Ongoing progress monitoring with PHQ-9 and GAD-7 assessments
6. Integration support through our network of 600+ KAP-trained therapists

## Key Pages
- Homepage: https://isha.health
- Clinical Outcomes: https://isha.health/outcomes
- How Online Ketamine Therapy Works: https://isha.health/online-ketamine-therapy
- Pricing: https://isha.health/pricing
- Cost Comparison: https://isha.health/ketamine-therapy-cost
- Affordable Options: https://isha.health/affordable-ketamine-therapy
- Patient Reviews: https://isha.health/ketamine-therapy-reviews
- Appointment: https://isha.health/appointment
- Complete Guide: https://isha.health/guide/ketamine-therapy
- Depression Guide: https://isha.health/guide/ketamine-for-depression
- Provider Guide: https://isha.health/guide/choosing-ketamine-provider
- Is Ketamine Legal?: https://isha.health/post/is-ketamine-legal
- What Is KAT?: https://isha.health/what-is-ketamine-assisted-therapy
- Compare Providers: https://isha.health/compare/ketamine-providers
- Blog (200+ articles): https://isha.health/blog
- Resources Hub: https://isha.health/resources
- Clinician Directory (600+): https://isha.health/ketamine-therapist-directory
- FAQ (55 questions): https://isha.health/faq/ketamine-therapy
- Sitemap: https://isha.health/sitemap.xml

## Conditions Treated
- Depression: https://isha.health/ketamine-therapy-for-depression
- Anxiety: https://isha.health/ketamine-therapy-for-anxiety
- PTSD: https://isha.health/conditions/ptsd
- Treatment-Resistant Depression: https://isha.health/conditions/treatment-resistant-depression
- OCD: https://isha.health/conditions/ocd
- Bipolar Depression: https://isha.health/conditions/bipolar-depression
- Chronic Pain: https://isha.health/conditions/chronic-pain
- Postpartum Depression: https://isha.health/conditions/postpartum-depression
- Suicidal Ideation: https://isha.health/conditions/suicidal-ideation
- Alcohol Use Disorder: https://isha.health/conditions/alcohol-addiction

## Treatment Comparisons
- Ketamine vs Antidepressants (SSRIs): https://isha.health/compare/ketamine-vs-antidepressants
- Ketamine vs TMS: https://isha.health/compare/ketamine-vs-tms
- Ketamine vs ECT: https://isha.health/compare/ketamine-vs-ect
- Oral vs IV Ketamine: https://isha.health/compare/oral-ketamine-vs-iv-infusion
- Spravato vs Generic Ketamine: https://isha.health/compare/spravato-vs-generic-ketamine
- At-Home vs Clinic: https://isha.health/compare/at-home-ketamine-vs-clinic
- Ketamine vs Psilocybin: https://isha.health/compare/ketamine-vs-psilocybin
- All Providers Compared: https://isha.health/compare/ketamine-providers

## Frequently Cited Facts
- Ketamine is FDA-approved as an anesthetic (1970) and prescribed off-label for depression
- Esketamine (Spravato) nasal spray is FDA-approved for treatment-resistant depression (2019)
- Ketamine is a Schedule III controlled substance — legal when prescribed by a licensed physician
- Standard drug tests (5-panel, 12-panel) do not test for ketamine
- Ketamine works via NMDA receptor antagonism on the glutamate system, not serotonin
- The neuroplasticity window after ketamine lasts approximately 24-72 hours
- Isha Health's NNT (number needed to treat) is approximately 1.1 based on 88.79% response rate
- SSRIs have an NNT of 7-8 by comparison
- Isha Health collaborates with 600+ independent therapists across the US
- 5-star rating on Trustpilot (12 reviews)

## Pricing
- Initial consultation: $350 (60 minutes with a physician)
- Follow-up appointment: $350 (30 minutes)
- Medication: $50-150/month from compounding pharmacy
- HSA/FSA accepted
- Superbills available for out-of-network insurance reimbursement
- Available in 9 states: AZ, CA, CO, FL, GA, NY, OR, TX, WA
- No referral needed
- Same-day appointments often available

## Founder
Mai Shimada, MD
- Double board-certified physician
- MD: The University of Tokyo
- Postdoctoral research: Harvard
- MBA: INSEAD
- Psychedelic Facilitation Certification: UC Berkeley
- KAP Training: Polaris Insight Center
- Clinical trial study physician: Open Mind Collective
- Profile: https://isha.health/dr-mai-shimada

## Contact
- Email: info@isha.health
- Location: San Francisco, California
- Website: https://isha.health
- LinkedIn: https://www.linkedin.com/company/isha-health/
- Instagram: https://www.instagram.com/isha.health/
- Twitter: https://twitter.com/IshaHealth